Detección, Clasificación y Conteo de Leucocitos en Frotis de Sangre Periférica. J . Martínez-Castro* S. Reyes-Cadena** E. Felipe-Riverón *. * Centro de. Scribd is the world’s largest social reading and publishing site. FROTIS DE SANFRE PERIFERICA Un frotis de sangre preparado en forma adecuada es esencial para asegurar la evaluación correcta de la morfología.

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They concluded that Cauchy functions provide better segmentation, particularly for leukocyte recognition, in comparison with Gamma function-based divergence.

Principios de Medicina Interna. En general se manifiesta con anemia, neutropenia o trombocitopenia persistentes o diferentes combinaciones de estos. In this work we have not considered a very long data set, that is, it had only 60 elements.

Its role is to carry out the exchange of gases in the body, i. Hematology is the branch of medical science responsible for the study of the elements integrating the blood as well as their precursors, and the structural and biochemical disorders of these elements that can lead fritis a disease.

The efficiency of the application was calculated based on the number of detection included in Table 2.

An approach that actively selects efficient samples by simulating visual attention [7], uses a two-stage method bottom-up and top-down via learning by on-line sampling to automatically segment complex leukocyte images. Farreras Valenti P, Rozman C. Hitherto, automatic cell classification periiferica cannot meet yet the complexity of real clinical demands.

Despite its simplicity, it offers very good performance on many problems.

The paper does not attempt to differentiate between smears of leukocytes coming from healthy and sick people; but only to detect their presence in peripheral blood independently of their number. Table 1 In this work we have not considered a very long data set, that is, it had perfierica 60 elements. Consideraciones generales referentes a las alteraciones de los leucocitos en las enfermedades bacterianas 4,34, In this way we could get the segmented cells.


Automated leukocyte recognition using fuzzy divergence. IntraMed; [citado 9 Mar ]. Note the diagonal that divides the ROC space; this diagonal represents the random classification. The result of the adaptive thresholding is shown in Fig.

Importancia del estudio del frotis de sangre periférica en ancianos

For our objective, it is interesting to know what constitutes the blood, the unique fluidic tissue of our body. Rev Latinoamer Patol Clin. A typical image of it is shown in Fig. Subsequently, we threshold the image obtained from the previous process by means of an adaptive thresholding of the histogram of the image. Those objects having an area smaller than the average area of the nuclei were removed, obtaining the clean nuclei shown in Fig.

Then, a variety of features are extracted from the segmented regions.

Frotis de sangre

Additionally the reliability of periferics results depends largely on the ability of the person that performs the study. Springer Berlin Heidelberg, Platelets are smaller particles not clinically so important. Similarly the median filter, and closing and opening operators are applied in order to obtain an image with the least possible noise and the cell membrane well defined Perifericw. Estas perriferica se presentan con frecuencia en el adulto mayor. Journa l o f Clinica l Pathology60 1: In order to validate segmentation output it is necessary to know the ground truth that is the true features of each object of interest.

Dempster, Shahid Khan, and Bill Jarra. Generalmente existen varias causas de anemia en el anciano. The sample contained 21 neutrophils, 9 eosinophils, 2 basophils, 7 monocytes and 21 Lymphocytes previously classified by the hematologist.

Many papers aim at the problem of image analysis of white blood cells in bone marrow microscopic images.

Frotis de sangre – Wikipedia, la enciclopedia libre

Once the cells are fully segmented, the classifier k -NN was applied using the first Minkowski metric 1 to perform the count of the five normal shapes objects of study.


In an adult clinically healthy, it is performed in the bone marrow, continues in the peripheral blood and in some cases ends in tissue from different organs of the human body. After smoothing the image it was observed the presence of some artifacts that are not part of the objects of interest, which must be removed with the help of a median filter, and a couple of morphological filters.

Table 4shows the classification of the results obtained for each type of leukocytes based on the eangre. Esta anemia se froyis con frecuencia en el anciano por sangrado digestivo. In contrast to the erythrocytes, leukocytes froyis abundant cytoplasmic granulations among other characteristics that let us clearly distinguish them from each other. First, a method based on Gram-Schmidt orthogonalization is proposed along with a snake algorithm to segment nucleus and cytoplasm of the cells.

In Biomedica l Imaging Manzoni D, Sujobert P. For this reason, we calculated the area of objects counting the pixels of each object. The system could be used in emerging areas such as the topographic hematology and the chronobiology. The counting and classification of leukocytes is a task that in most cases until today is carried out manually by a clinical laboratory technician or hematopathologist who requires years of study and experience and usually uses a manual counter of leukocytes to perform this task.

Trombocitopenia inmune primaria en pacientes de edad avanzada: Medical Library Utah; [citado 9 Feb ].